Description

2-Chloro-1-(2-Methyl-2,3-Dihydro-Indol-1-Yl)-Ethanone is a versatile and high-purity organic building block, specifically an N-acyl indoline derivative. This compound matters as a critical synthetic intermediate for constructing complex heterocyclic frameworks, enabling the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for lead optimization and scalable synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of indole-based drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators with indoline scaffolds.
• Organic Synthesis Reagent: Used in academic and industrial research for constructing complex nitrogen-containing heterocycles via further functionalization.
• Material Science Research: Potential monomer or precursor for specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe Development: Serves as a core structure for creating molecular probes to study biological pathways.

Basic Information

Product Name	2-Chloro-1-(2-Methyl-2,3-Dihydro-Indol-1-Yl)-Ethanone
CAS No.	1013-18-9
Molecular Formula	C11H12ClNO
Molecular Weight	209.67 g/mol
Synonyms	1-(2-Chloroacetyl)-2-methylindoline; 2-Chloro-1-(2-methylindolin-1-yl)ethanone; 2-Chloro-1-(2-methyl-2,3-dihydro-1H-indol-1-yl)ethanone; 2-Methyl-1-(2-chloroacetyl)indoline; N-(2-Chloroacetyl)-2-methylindoline; α-Chloro-2-methylindolin-1-yl methyl ketone
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(2-Methyl-2,3-Dihydro-Indol-1-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.