Description

2-Bromothiophene is a versatile halogenated heterocyclic building block essential for advanced organic synthesis. Its primary value lies in its reactivity, serving as a key intermediate for constructing complex molecules in pharmaceuticals and agrochemicals. This compound is particularly critical for researchers and manufacturers in the fine chemical, pharmaceutical, and material science industries who require high-purity intermediates for coupling reactions and functional group transformations.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing thiophene scaffolds.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and insecticides, where the bromothiophene moiety imparts specific biological activity.
• Material Science & Organic Electronics: Serves as a monomer or building block for conductive polymers, organic semiconductors, and non-linear optical materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions to form biaryl and other complex structures.
• Ligand & Catalyst Preparation: Utilized in the development of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Bromothiophene
CAS No.	1003-09-4
Molecular Formula	C4H3BrS
Molecular Weight	163.03 g/mol
Synonyms	Thiophene, 2-bromo-; 2-Bromothiophene; α-Bromothiophene; 2-Thienyl bromide; Bromothiophene; 2-Bromo-thiophene; 2-BT; NSC 404087
EINECS	213-710-5

Quality Control

Our 2-Bromothiophene is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.