Description

4-Chlorobenzyl Cyanide is a versatile aromatic nitrile building block of significant importance in advanced organic synthesis. Its core value lies in its bifunctional structure, featuring both a reactive benzylic chloromethyl group and a cyano group, enabling its use in the construction of complex pharmaceutical intermediates and agrochemicals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), including antidepressants, antihistamines, and other biologically active molecules.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the chlorobenzyl moiety is incorporated into the final product's structure.
• Ligand and Catalyst Preparation: Serves as a starting material for the synthesis of specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of certain high-performance dyes and organic pigments.
• Polymer Modification: Can be used to introduce cyano and aromatic functionalities into polymer chains to modify thermal and mechanical properties.
• Organic Synthesis Building Block: Employed in nucleophilic substitution reactions, cyano group transformations, and as a scaffold for heterocyclic compound synthesis.

Basic Information

Product Name	4-Chlorobenzyl Cyanide
CAS No.	140-53-4
Molecular Formula	C8H6ClN
Molecular Weight	151.59 g/mol
Synonyms	(4-Chlorophenyl)acetonitrile; p-Chlorobenzyl Cyanide; 4-Chlorophenylacetonitrile; 2-(4-Chlorophenyl)acetonitrile; α-Chloro-p-tolunitrile; p-Chlorobenzeneacetonitrile; NSC 9245; 4-Chlorobenzeneacetonitrile
EINECS	205-427-7

Quality Control

Our 4-Chlorobenzyl Cyanide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global customer base. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee supply reliability and product traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizers, strong acids, and strong bases. Recommended storage temperature is between 15°C and 25°C. The product is moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	28°C - 32°C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.