Lipid Regulators
Circulatory System Drugs
- Lipid Regulators
- Antianginals
- Calcium Channel Blockers
- Anticongestive Heart Failure Drugs
- Antihypertensives
- Antiarrhythmics
- Shock Vasoactive Drugs
- Other Cardiovascular Drugs
- ACE Inhibitors and ARBs
- Peripheral Vasodilators
- β-Adrenergic Receptor Blockers
- Chronic Heart Failure Therapeutics
- Antiatherosclerotic Drugs
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Lipid Regulators
Lipid regulators are therapeutic agents used to lower elevated cholesterol and triglyceride levels, prevent atherosclerosis progression, and reduce cardiovascular risk. Major classes include statins, fibrates, bile acid sequestrants, niacin, and cholesterol absorption inhibitors. Statins remain the cornerstone due to their potent inhibition of HMG-CoA reductase, leading to reduced LDL levels and improved endothelial function. Fibrates primarily target triglyceride reduction by activating PPAR-α, while niacin improves HDL levels and decreases hepatic lipid synthesis. These medications are widely used in dyslipidemia, metabolic syndrome, diabetes, and secondary prevention of cardiovascular events. Proper monitoring is required to avoid adverse effects such as hepatotoxicity, myopathy, or metabolic disturbances. Lipid regulators play a central role in long-term cardiovascular protection.
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