Nitrofurans

Nitrofurans

Nitrofurans are synthetic antimicrobial agents characterized by a nitrofuran ring that undergoes intracellular reduction to generate reactive intermediates capable of damaging bacterial DNA, ribosomal proteins, and metabolic enzymes. These drugs, including nitrofurantoin, furazolidone, and nitrofurazone, exhibit broad-spectrum activity against Gram-positive and Gram-negative bacteria, particularly in urinary and gastrointestinal infections. Nitrofurantoin remains a first-line therapy for uncomplicated urinary tract infections due to its high urinary concentrations and limited systemic distribution. Nitrofurans act through multiple mechanisms, reducing the risk of resistance, although long-term use may be limited by pulmonary, hepatic, or neurological toxicity. Despite safety considerations, nitrofurans remain valuable in both human and veterinary medicine due to their efficacy and low cross-resistance potential.

Nifurimide CAS NO 15179-96-1

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CAS No.:15179-96-1

Grade:Pharmacy Grade

Content:99.90%

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Nitrofurantoin1-Hydrate CAS NO 17140-81-7

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CAS No.:17140-81-7

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12Dihydro25Nitrofuryl4Hydroxychinazolin3Oxide CAS NO 17247-77-7

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CAS No.:17247-77-7

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Nitrofarin CAS NO 17298-36-1

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CAS No.:17298-36-1

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Content:99.90%

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Nifurmazole CAS NO 18857-59-5

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CAS No.:18857-59-5

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Content:99.90%

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Magnesium Mandelate CAS NO 18937-33-2

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CAS No.:18937-33-2

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Content:99.90%

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Nifuratrone CAS NO 19561-70-7

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CAS No.:19561-70-7

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Content:99.90%

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n-(4-Chlorophenyl)-5-Nitrofuran-2-Carboxamide CAS NO 109844-92-0

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CAS No.:109844-92-0

Grade:Pharmacy Grade

Content:99.90%

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