Nitrofurans

Synthetic Anti-Infective Drugs

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Nitrofurans

Nitrofurans are synthetic antimicrobial agents characterized by a nitrofuran ring that undergoes intracellular reduction to generate reactive intermediates capable of damaging bacterial DNA, ribosomal proteins, and metabolic enzymes. These drugs, including nitrofurantoin, furazolidone, and nitrofurazone, exhibit broad-spectrum activity against Gram-positive and Gram-negative bacteria, particularly in urinary and gastrointestinal infections. Nitrofurantoin remains a first-line therapy for uncomplicated urinary tract infections due to its high urinary concentrations and limited systemic distribution. Nitrofurans act through multiple mechanisms, reducing the risk of resistance, although long-term use may be limited by pulmonary, hepatic, or neurological toxicity. Despite safety considerations, nitrofurans remain valuable in both human and veterinary medicine due to their efficacy and low cross-resistance potential.

[[4-Methyl-5-(5-Nitro-2-Furyl)-4H-1,2,4-Triazol-3-Yl]Amino]Methanol CAS NO 23633-05-8

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CAS No.:23633-05-8

Grade:Pharmacy Grade

Content:99.90%

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[[1-Methyl-3-(5-Nitro-2-Furyl)-1H-1,2,4-Triazol-5-Yl]Amino]Methanol CAS NO 24054-57-7

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CAS No.:24054-57-7

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Content:99.90%

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Acetamide,n-(3,5-Nitro-2-Furyl)-1,2,4-Oxadiazinyl- CAS NO 24143-08-6

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CAS No.:24143-08-6

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Content:99.90%

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Nifurpipone CAS NO 24632-47-1

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CAS No.:24632-47-1

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Content:99.90%

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N'-[(5-Nitrofuran-2-Yl)Methylene]-4-Dodecyl-1-Piperazineacetic Acid Hydrazide CAS NO 24632-53-9

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CAS No.:24632-53-9

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Content:99.90%

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N'-[(5-Nitrofuran-2-Yl)Methylene]-4-[(Diethylamino)Carbonyl]-1-Piperazineacetic Acid Hydrazide CAS NO 24632-55-1

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CAS No.:24632-55-1

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N'-[(5-Nitrofuran-2-Yl)Methylene]-4-Acetyl-1-Piperazineacetic Acid Hydrazide CAS NO 24632-58-4

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CAS No.:24632-58-4

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Content:99.90%

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N'-[(5-Nitrofuran-2-Yl)Methylene]-4-(2-Hydroxyethyl)-1-Piperazineacetic Acid Hydrazide CAS NO 24632-59-5

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CAS No.:24632-59-5

Grade:Pharmacy Grade

Content:99.90%

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