Polyenes

Polyenes

Polyenes are antifungal antibiotics characterized by multiple conjugated double bonds that bind to ergosterol in fungal cell membranes, causing pore formation and cell death. Major agents include amphotericin B and nystatin, which exhibit broad-spectrum activity against yeasts, molds, and systemic fungal pathogens. Polyenes are indispensable for treating life-threatening infections such as cryptococcal meningitis and systemic candidiasis. While highly effective, traditional formulations of amphotericin B are associated with nephrotoxicity, leading to development of lipid-based delivery systems that improve safety and therapeutic index. Polyenes are formulated as injectables, topical creams, and oral suspensions, and remain central to antifungal pharmacotherapy.

n-(N'-(2-(4'-Methylmorpholinio)Ethyl)-N''-Cyclohexylguanyl)Amphotericin B Methyl Ester CAS NO 79451-27-7

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CAS No.:79451-27-7

Grade:Pharmacy Grade

Content:99.90%

Packaging:Customizable

Mysteclin-Ovula CAS NO 8013-46-5

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CAS No.:8013-46-5

Grade:Pharmacy Grade

Content:99.90%

Packaging:Customizable

Aureofungin A CAS NO 8065-41-6

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CAS No.:8065-41-6

Grade:Pharmacy Grade

Content:99.90%

Packaging:Customizable

Cationomycin CAS NO 80394-65-6

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CAS No.:80394-65-6

Grade:Pharmacy Grade

Content:99.90%

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Cannitracin CAS NO 84930-92-7

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CAS No.:84930-92-7

Grade:Pharmacy Grade

Content:99.90%

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Fungichromin CAS NO 6834-98-6

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CAS No.:6834-98-6

Grade:Pharmacy Grade

Content:99.90%

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Myxalamid B CAS NO 86934-10-3

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CAS No.:86934-10-3

Grade:Pharmacy Grade

Content:99.90%

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Tetrafungin CAS NO 87502-38-3

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CAS No.:87502-38-3

Grade:Pharmacy Grade

Content:99.90%

Packaging:Customizable

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