Description

Dichloro{(R)-(+)-5,5'-bis[di(3,5-xylyl)phosphino]-4,4'-bi-1,3-benzodioxole}[(1R,2R)-(+)-1,2-diphenylethylenediamine]ruthenium(II), also known as RuCl2[(R)-dm-segphos][(R,R)-dpen], is a highly specialized chiral ruthenium complex designed for asymmetric hydrogenation and other enantioselective transformations. This catalyst is critical for achieving high enantiomeric excess (ee) in the synthesis of complex pharmaceutical intermediates and fine chemicals. It is an essential tool for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and functionalized olefins to produce chiral alcohols, amines, and other building blocks.
• Pharmaceutical Intermediate Synthesis: Key catalyst in the production of active pharmaceutical ingredients (APIs) requiring specific chirality, such as β-amino acids and chiral amines.
• Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Enables the creation of high-value chiral compounds for flavors, fragrances, and specialty materials.
• Academic and Industrial R&D: A valuable reagent for methodology development and exploring new enantioselective reaction pathways.
• Process Chemistry Optimization: Employed in scaling up efficient and selective catalytic processes for commercial manufacturing.

Basic Information

Product Name	Dichloro{(R)-(+)-5,5'-bis[di(3,5-xylyl)phosphino]-4,4'-bi-1,3-benzodioxole}[(1R,2R)-(+)-1,2-diphenylethylenediamine]ruthenium(II)
CAS No.	944450-45-7
Molecular Formula	C78H72Cl2N2O4P2Ru
Molecular Weight	1309.78 g/mol
Synonyms	RuCl2[(R)-dm-segphos][(R,R)-dpen]; Dichloro[(R)-5,5'-bis[di(3,5-xylyl)phosphino]-4,4'-bi-1,3-benzodioxole][(1R,2R)-1,2-diphenylethylenediamine]ruthenium; (R,R)-DPEN-RuCl2-(R)-DM-SEGPHOS; Ruthenium(II) dichloro complex with (R)-DM-SEGPHOS and (R,R)-DPEN; Asymmetric Hydrogenation Catalyst Ru-DM-SEGPHOS-DPEN; RuCl2[(R)-DM-SEGPHOS][(R,R)-DPEN]; [RuCl2((R)-dm-segphos)((R,R)-dpen)]; CAS 944450-45-7
EINECS	Contact for details

Quality Control

Our chiral catalyst is produced under strict quality-controlled conditions to ensure batch-to-batch consistency and optimal catalytic performance. Each lot is characterized by advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specifications such as Ru content, ligand-to-metal ratio, and enantiomeric purity are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (argon or nitrogen) to maintain stability and catalytic activity. Keep away from oxidizing agents and strong acids.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Ruthenium (Ru) Content	Contact for details
Solubility	Soluble in common organic solvents (DCM, THF, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.