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[1,1'-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium(Ii) CAS NO 72287-26-4
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CAS No.:72287-26-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
[1,1'-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium(II) is a highly versatile and efficient palladium-based catalyst, widely recognized for its stability and excellent ligand properties. This compound is crucial for enabling a wide range of cross-coupling reactions, which are fundamental to constructing complex organic molecules in modern synthetic chemistry. It is an essential reagent for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors.
Application
- Suzuki-Miyaura Cross-Coupling Reactions: A premier catalyst for forming carbon-carbon bonds between aryl/vinyl boronic acids and aryl/vinyl halides, critical for pharmaceutical intermediate synthesis.
- Negishi Coupling: Effective in coupling organozinc reagents with organic halides for the production of fine chemicals and complex natural products.
- Buchwald-Hartwig Amination: Facilitates carbon-nitrogen bond formation for creating aryl amines, key structures in many active pharmaceutical ingredients (APIs).
- Heck Reaction (Mizoroki-Heck): Catalyzes the coupling of alkenes with aryl or vinyl halides for synthesizing substituted alkenes used in materials science.
- Polymer and Materials Science: Used in the synthesis of conductive polymers, OLED materials, and other advanced functional materials requiring precise molecular architecture.
- Asymmetric Synthesis: Serves as a catalyst precursor for chiral transformations when used with appropriate chiral ligands, important for producing enantiomerically pure compounds.
- Academic and Industrial R&D: A staple catalyst in research laboratories for methodological development and the synthesis of novel chemical entities.
- Scale-up and Process Chemistry: Valued for its robustness and consistent performance in transitioning reactions from laboratory to pilot and production scale.
Basic Information
| Item | Detail |
|---|---|
| Product Name | [1,1'-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium(II) |
| CAS No. | 72287-26-4 |
| Molecular Formula | C34H28Cl2FeP2Pd |
| Molecular Weight | 731.69 g/mol |
| Synonyms | Pd(dppf)Cl2; [1,1'-Bis(diphenylphosphino)ferrocene]palladium(II) dichloride; Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II); Palladium(II) dichloride with 1,1'-bis(diphenylphosphino)ferrocene; DPPF-PdCl2; PdCl2(dppf); [PdCl2(dppf)]; (Dppf)PdCl2 |
| EINECS | Contact for details |
Quality Control
Our [1,1'-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium(II) is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic activity. Each lot undergoes comprehensive analytical testing, including NMR, elemental analysis (EA), and HPLC, to verify identity, purity, and the absence of deleterious impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal catalytic performance. Keep away from incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | Orange to red-brown crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Pd Content | 14.0 - 15.0 % |
| Solubility | Soluble in dichloromethane, toluene; slightly soluble in THF |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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