Description

1H-Benz[e]indene-3-acetic acid, 6-(2-carboxyethyl)-2,3,3a,4,6,7,8,9b-octahydro-3a,6,9b-trimethyl-7-(1-methylethenyl)-α-(4-methyl-3-penten-1-yl)-, (αR,3R,3aR,6S,7S,9bR)- is a complex, high-purity chiral intermediate with a defined stereochemistry that is critical for advanced synthesis. This compound is valued for its role as a sophisticated building block in the research and development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by pharmaceutical R&D laboratories, specialty chemical manufacturers, and academic research institutions working on complex organic synthesis and drug discovery projects.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel, high-value active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures.
• Organic Synthesis Research: Serves as a critical building block in academic and industrial research for developing new synthetic methodologies and exploring complex chemical spaces.
• Fine Chemical Production: Used in the manufacture of specialty and custom fine chemicals where precise stereochemistry and high purity are paramount.
• Asymmetric Catalysis Studies: Employed as a substrate or ligand precursor in the development and testing of new asymmetric catalytic reactions.
• Reference Standard: Provides a high-purity, structurally defined compound for use as an analytical reference standard in quality control and method development.

Basic Information

Product Name	1H-Benz[e]indene-3-acetic acid, 6-(2-carboxyethyl)-2,3,3a,4,6,7,8,9b-octahydro-3a,6,9b-trimethyl-7-(1-methylethenyl)-α-(4-methyl-3-penten-1-yl)-, (αR,3R,3aR,6S,7S,9bR)-
CAS No.	943225-55-6
Molecular Formula	C31H44O4
Molecular Weight	480.68 g/mol
Synonyms	(αR,3R,3aR,6S,7S,9bR)-6-(2-Carboxyethyl)-2,3,3a,4,6,7,8,9b-octahydro-3a,6,9b-trimethyl-7-(1-methylethenyl)-α-(4-methyl-3-penten-1-yl)-1H-benz[e]indene-3-acetic acid; (5R,8R,8aR,11S,12S,14aR)-5,8,8a-Trimethyl-11-(1-methylethenyl)-8a-(4-methyl-3-penten-1-yl)perhydro-1H-benz[e]indene-3a,6(2H)-dicarboxylic acid; A complex diterpenoid-derived acid intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all relevant specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.