Description

2-Chloro-4-Fluoro-5-Nitrobenzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. This compound matters because its unique halogen and nitro substitution pattern makes it a versatile intermediate for constructing complex molecules with tailored properties. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated and nitro-substituted aromatic rings.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the chloro-fluoro-nitro motif can enhance biological activity.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the development of novel colorants and functional dyes due to its nitro and halogen substituents.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig amination, enabling rapid diversification of chemical libraries.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.

Basic Information

Product Name	2-Chloro-4-Fluoro-5-Nitrobenzoic Acid
CAS No.	114776-15-7
Molecular Formula	C7H3ClFNO4
Molecular Weight	219.55 g/mol
Synonyms	5-Nitro-2-chloro-4-fluorobenzoic Acid; Benzoic acid, 2-chloro-4-fluoro-5-nitro-; 2-Chloro-4-fluoro-5-nitro-benzoic acid; 114776-15-7; 2-Chloro-4-fluoro-5-nitrobenzoic acid; 4-Fluoro-2-chloro-5-nitrobenzoic acid; 2-Chloro-4-fluoro-5-nitrobenzoic acid (CAS 114776-15-7)
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-5-Nitrobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.