Description

5-chloro-7-iodo-quinolin-8-ol, [2-[(8S,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] propanoate is a sophisticated, high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This complex steroid-quinoline hybrid compound is designed for use in the synthesis of novel therapeutic agents, offering a unique structural scaffold for drug discovery. It is primarily targeted at research institutions and pharmaceutical companies engaged in developing next-generation steroid-based or receptor-targeting medications.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel steroid derivatives with potential therapeutic activity.
• Drug Discovery & Medicinal Chemistry: Serves as a key precursor for creating targeted molecular libraries to screen for biological activity against specific disease pathways.
• Research Chemical: Used in academic and industrial R&D settings to study structure-activity relationships (SAR) and metabolic pathways of complex heterocyclic-steroid conjugates.
• API (Active Pharmaceutical Ingredient) Development: Employed in the development and scale-up processes for potential new active pharmaceutical ingredients, particularly in oncology and endocrinology.
• Biochemical Probe Synthesis: Utilized to create labeled or modified probes for investigating steroid hormone receptor interactions and signaling mechanisms.

Basic Information

Product Name	5-chloro-7-iodo-quinolin-8-ol, [2-[(8S,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] propanoate
CAS No.	93281-21-1
Molecular Formula	C34H38ClFINO7
Molecular Weight	738.02 g/mol
Synonyms	9-Fluoro-11β,17-dihydroxy-17-(2-(propionyloxy)acetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one 17-propionate 8-(5-chloro-7-iodo-8-quinolyl) ether; 5-Chloro-7-iodo-8-quinolyl 9-fluoro-11β,17,21-trihydroxy-10,13,16-trimethyl-20-oxo-1,4-pregnadiene-3,11-dicarboxylate derivative; Steroid-Quinoline Hybrid Intermediate; CAS 93281-21-1; 8-Hydroxy-5-chloro-7-iodoquinoline steroid ester
EINECS	Contact for details

Quality Control

This high-value intermediate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and purity suitable for research and development. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with exacting standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.