Description

(R)-(-)-1,3-Butanediol CAS NO 6290-03-5 is a high-purity, chiral diol characterized by its specific (R)-enantiomeric configuration. This stereochemical purity makes it a critical chiral building block and solvent for advanced research and manufacturing processes where molecular handedness is essential. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis, chiral resolution, and as a precursor for high-value intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of enantiomerically pure drugs.
• Asymmetric Synthesis: Used as a chiral auxiliary or solvent in stereoselective reactions to induce desired chirality in target molecules.
• Agrochemicals: Serves as a precursor in the manufacture of chiral pesticides and herbicides, where the specific enantiomer can dictate biological activity.
• Polymer Chemistry: Employed in the production of specialized polyesters and polyurethanes with tailored properties derived from its chiral center.
• Cosmetics & Personal Care: Functions as a humectant and solvent in high-end cosmetic formulations, valued for its purity and mild properties.
• Flavor & Fragrance Industry: Acts as a starting material or carrier for the synthesis of chiral aroma compounds.
• Laboratory Research: An essential reagent in academic and industrial R&D for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(R)-(-)-1,3-Butanediol
CAS No.	6290-03-5
Molecular Formula	C4H10O2
Molecular Weight	90.12 g/mol
Synonyms	(R)-1,3-Butylene Glycol; (R)-1,3-Dihydroxybutane; (R)-(-)-1,3-Butanediol; (R)-1,3-BD; (R)-Butane-1,3-diol; (R)-1,3-Butanediol; (R)-β-Hydroxybutyraldehyde Dimer; (R)-1,3-Butylenglykol
EINECS	228-526-5

Quality Control

Our (R)-(-)-1,3-Butanediol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the stringent requirements for chiral intermediates. Certificates of Analysis (COA) detailing specific results for enantiomeric excess (e.e.), chemical purity, and identity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Enantiomeric Excess (e.e.) (Chiral GC/HPLC)	≥ 99.0%
Specific Rotation [α]20/D	-20° to -24° (c=1, H2O)
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.438 - 1.442
Density (20°C)	1.005 - 1.015 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.