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1-Chloro-2-(1-Chlorocyclopropyl)-3-(2-Chlorophenyl)Propan-2-Ol CAS NO 134818-67-0
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CAS No.:134818-67-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-Chloro-2-(1-Chlorocyclopropyl)-3-(2-Chlorophenyl)Propan-2-Ol is a specialized chlorinated organic compound featuring a cyclopropane ring and a phenyl group, making it a valuable and versatile chiral building block for advanced chemical synthesis. Its complex structure is engineered to serve as a critical intermediate in the development of high-value active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific stereochemistry and functional groups into complex molecules.
Application
- Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
- Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced pesticides and herbicides, where the chlorinated cyclopropyl moiety contributes to biological activity.
- Fine Chemical Production: Used in custom synthesis and contract manufacturing for producing complex, high-purity specialty chemicals.
- Research & Development: Employed in academic and industrial laboratories for methodological studies in organic synthesis, including asymmetric catalysis and ring-opening reactions.
- Material Science Precursor: Potential use in synthesizing functionalized monomers or ligands for advanced polymeric materials and catalysts.
Basic Information
| Product Name | 1-Chloro-2-(1-Chlorocyclopropyl)-3-(2-Chlorophenyl)Propan-2-Ol |
| CAS No. | 134818-67-0 |
| Molecular Formula | C12H13Cl3O |
| Molecular Weight | 279.59 g/mol |
| Synonyms | 1-Chloro-2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propan-2-ol; 2-Propanol, 1-chloro-2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-; α-(1-Chlorocyclopropyl)-2-chlorobenzyl alcohol, 1-chloro derivative; (2-Chlorophenyl)[1-chloro-1-(chloromethyl)cyclopropyl]methanol; CAS 134818-67-0 |
| EINECS | Contact for details |
Quality Control
Our 1-Chloro-2-(1-Chlorocyclopropyl)-3-(2-Chlorophenyl)Propan-2-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay, enantiomeric excess (if applicable), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of multiple functional groups, it is advisable to store under an inert atmosphere for long-term stability and to minimize potential degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Specific Impurities (HPLC) | Individual ≤ 0.5%, Total ≤ 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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