Description

(Z)-2-Methyl-2-butenoic acid (3aR)-7α-(acetyloxy)-2,3,3aβ,4,5,7,7aα,8a,8b,8cα-decahydro-4β,8bβ-dihydroxy-6,8aα-dimethyl-3-methylene-2-oxooxireno[2,3]azuleno[4,5-b]furan-5α-yl ester is a high-purity, complex diterpenoid derivative with a defined stereochemistry, serving as a critical advanced pharmaceutical intermediate and a valuable scaffold for chemical synthesis. Its intricate fused-ring structure makes it an essential building block for research and development in medicinal chemistry, particularly for exploring novel bioactive compounds. This product is primarily targeted at pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex natural product analogs and specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral precursor in the multi-step synthesis of complex drug candidates and natural product derivatives.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Synthetic Organic Chemistry: Serves as a sophisticated starting material or intermediate for synthesizing complex polycyclic compounds in academic and industrial research.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Biochemical Probe Development: Utilized in the design and synthesis of molecular probes for studying biological pathways and target interactions.

Basic Information

Product Name	(Z)-2-Methyl-2-butenoic acid (3aR)-7α-(acetyloxy)-2,3,3aβ,4,5,7,7aα,8a,8b,8cα-decahydro-4β,8bβ-dihydroxy-6,8aα-dimethyl-3-methylene-2-oxooxireno[2,3]azuleno[4,5-b]furan-5α-yl ester
CAS No.	90734-99-9
Molecular Formula	C24H30O8
Molecular Weight	446.49 g/mol
Synonyms	7α-Acetoxy-2,3,3aβ,4,5,7,7aα,8a,8b,8cα-Decahydro-4β,8bβ-dihydroxy-6,8aα-dimethyl-3-methylene-2-oxooxireno[2,3]azuleno[4,5-b]furan-5α-yl (Z)-2-methyl-2-butenoate; Tiglic acid ester of a diterpenoid oxirenoazulenofuran derivative; CAS 90734-99-9; (3aR,4S,5S,7S,7aS,8aR,8bS,8cS)-7-(Acetyloxy)-4,8b-dihydroxy-6,8a-dimethyl-3-methylidene-2-oxo-3a,4,5,6,7,7a,8,8a,8b,8c-decahydrooxireno[2,3]azuleno[4,5-b]furan-5-yl (2Z)-2-methylbut-2-enoate
EINECS	Contact for details

Quality Control

Our (Z)-2-Methyl-2-butenoic acid diterpenoid ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, chiral analysis to confirm stereochemical integrity, and identification via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. The compound may be sensitive to moisture and prolonged exposure to elevated temperatures.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.