Description

(3aS,4S,5R,6E,10E,11aS)-4,5-Bis(2-methylpropionyloxy)-10-(hydroxymethyl)-2-oxo-3-methylene-2,3,3a,4,5,8,9,11a-octahydrocyclodeca[b]furan-6-carboxylic acid methyl ester is a complex, high-purity organic compound with a defined stereochemistry, serving as a critical advanced pharmaceutical intermediate or reference standard. Its intricate structure makes it a valuable building block for the synthesis of novel therapeutic agents, particularly in oncology and anti-inflammatory research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and fine chemical industries seeking to develop new drug candidates or analytical methods.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for complex natural product derivatives.
• Reference Standard: Used for analytical method development, validation, and quality control (HPLC, LC-MS) in pharmaceutical laboratories.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new biological targets and optimize lead compounds.
• Process Chemistry: Serves as a starting material or intermediate in scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in university and institutional labs for studying organic synthesis methodologies, particularly those involving furan and cyclodecane frameworks.

Basic Information

Item	Detail
Product Name	(3aS,4S,5R,6E,10E,11aS)-4,5-Bis(2-methylpropionyloxy)-10-(hydroxymethyl)-2-oxo-3-methylene-2,3,3a,4,5,8,9,11a-octahydrocyclodeca[b]furan-6-carboxylic acid methyl ester
CAS No.	89900-56-1
Molecular Formula	C25H34O9
Molecular Weight	478.53 g/mol
Synonyms	Methyl (3aS,4S,5R,6E,10E,11aS)-4,5-diisobutyryloxy-10-(hydroxymethyl)-2-oxo-3-methylidene-2,3,3a,4,5,8,9,11a-octahydrocyclodeca[b]furan-6-carboxylate; 4,5-Diisobutyryloxy-10-hydroxymethyl-2-oxo-3-methylene-2,3,3a,4,5,8,9,11a-octahydrocyclodeca[b]furan-6-carboxylic Acid Methyl Ester; Cyclodeca[b]furan-6-carboxylic acid derivative; CAS 89900-56-1
EINECS	Contact for details

Quality Control

Our (3aS,4S,5R,6E,10E,11aS)-4,5-Bis(2-methylpropionyloxy)-10-(hydroxymethyl)-2-oxo-3-methylene-2,3,3a,4,5,8,9,11a-octahydrocyclodeca[b]furan-6-carboxylic acid methyl ester is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under inert atmosphere at lower temperatures (e.g., -20°C) to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.