Description

(2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxy-furan-3-one, (3R,4S,5S, 6R,7R,9R,11R,12R,13R,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6 -methyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-h ydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1 -oxacyclotetradecane-2,10-dione is a complex, high-purity macrolide compound of significant interest in advanced pharmaceutical research and development. Its intricate stereochemistry and functional groups make it a valuable key intermediate for synthesizing novel therapeutic agents, particularly in the antibiotic and anti-parasitic domains. This product is essential for R&D laboratories, process chemists, and pharmaceutical manufacturers engaged in the development of next-generation macrolide derivatives.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel macrolide antibiotics and anti-parasitic agents.
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Utilized in studies investigating the mechanism of action and resistance of macrolide-class compounds.

Basic Information

Product Name	(2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxy-furan-3-one, (3R,4S,5S, 6R,7R,9R,11R,12R,13R,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6 -methyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-h ydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1 -oxacyclotetradecane-2,10-dione
CAS No.	7690-37-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Erythromycin derivative; Macrolide intermediate 7690-37-1; Erythromycin A 6,9-hemiketal; 6,9-Hemiketal of Erythromycin A; 9(S)-Erythromycylamine 6,9-hemiketal; Erythromycin 6,9-cyclic ketal; CAS 7690-37-1
EINECS	Contact for details

Quality Control

Our (2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxy-furan-3-one, (3R,4S,5S, 6R,7R,9R,11R,12R,13R,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6 -methyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-h ydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1 -oxacyclotetradecane-2,10-dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identification, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.