Description

Erythromycin Ethylsuccinate CAS NO 1264-62-6 is a macrolide antibiotic ester, specifically the ethylsuccinate salt of erythromycin, designed to enhance solubility and bioavailability. This compound is a critical active pharmaceutical ingredient (API) and intermediate, valued for its broad-spectrum antibacterial efficacy against Gram-positive and some Gram-negative organisms. It is essential for manufacturers in the pharmaceutical industry producing oral suspensions, tablets, and other dosage forms for human and veterinary medicine.

Application

• Pharmaceutical API: Primary use as the active ingredient in oral antibiotic formulations, particularly pediatric suspensions due to its improved taste-masking properties.
• Veterinary Medicine: Used in the production of antibiotics for treating bacterial infections in livestock, poultry, and companion animals.
• Intermediate Synthesis: Serves as a key precursor in the synthesis of other erythromycin derivatives and more complex macrolide antibiotics.
• Clinical Research: Employed as a reference standard in pharmaceutical R&D, quality control laboratories, and pharmacokinetic studies.
• Generic Drug Manufacturing: A vital component for companies producing generic versions of erythromycin-based medications.

Basic Information

Product Name	Erythromycin Ethylsuccinate
CAS No.	1264-62-6
Molecular Formula	C43H75NO16
Molecular Weight	862.06 g/mol
Synonyms	Erythromycin Ethyl Succinate; Erythromycin 2'-Ethylsuccinate; EryPed; E.E.S.; Erythrocin Ethyl Succinate; Erythromycin 8-Ethylsuccinate; CAS 1264-62-6; Ilosone (for the ethylsuccinate salt formulation)
EINECS	215-025-7

Quality Control

Our Erythromycin Ethylsuccinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards, including compliance with USP, EP, and CP pharmacopoeial monographs where applicable. A detailed Certificate of Analysis (COA) documenting identity, purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	95.0% - 102.0% (on anhydrous basis)
Water (Karl Fischer)	≤ 3.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 5.0% Any individual impurity ≤ 2.0%
Specific Rotation	-70° to -78° (c=1 in CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.