Description

Spiramycin, Hexanedioate CAS NO 11034-40-5 is the adipic acid salt form of the macrolide antibiotic spiramycin, offering enhanced stability and handling properties. This compound is valued for its broad-spectrum antibacterial activity, particularly against Gram-positive bacteria and certain intracellular pathogens. It is a critical active pharmaceutical ingredient (API) for the formulation of veterinary and, in some regions, human medicinal products targeting bacterial infections.

Application

• Veterinary Pharmaceutical API: Primary use in the manufacture of injectable, oral, and topical formulations for treating bacterial infections in livestock, poultry, and companion animals.
• Aquaculture Treatments: Used in medicated feeds or baths to control bacterial diseases in farmed fish and shellfish.
• Human Pharmaceutical Intermediates: Serves as a key starting material or intermediate in the synthesis of other macrolide antibiotic derivatives for human use, subject to regional regulatory approvals.
• Research & Development: Utilized in microbiological and pharmacological research as a reference standard or for studying antibiotic mechanisms of action and resistance.
• Feed Additive Precursor: Employed in the production of specialized feed additives for growth promotion and disease prevention in animal husbandry, adhering to local regulatory frameworks.

Basic Information

Product Name	Spiramycin, Hexanedioate
CAS No.	11034-40-5
Molecular Formula	C45H78N2O16 • C6H10O4
Molecular Weight	~ 1015.2 g/mol (as salt)
Synonyms	Spiramycin Adipate; Spiramycin Hexanedioate Salt; Foromacidin A Adipate; Rovamycin Adipate; Sequamycin Adipate; Spiramycin I, II, III Adipate Mixture; Antibiotic 5337 Adipate; Provamycin Adipate; Selectomycin Adipate
EINECS	Contact for details

Quality Control

Our Spiramycin, Hexanedioate is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets stringent specifications for pharmaceutical use. Quality assurance includes testing for identity, purity, potency, and specific impurities. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing results against relevant pharmacopoeial standards (such as EP, USP, or CP) where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%
Specific Optical Rotation	-80° to -90° (c=1 in water)
pH (in solution)	6.0 - 8.0
Microbial Limits	Meets requirements for absence of specified pathogens

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.