Description

1H-Indeno[5,4-f]quinoline-7-carboxylic acid, 3-fluoro-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1,4a,6a-triMethyl-2-oxo-, Methyl ester, (4aS,4bS,6aS,7S,9aS,9bS,11aR)- is a complex, stereochemically defined fluorinated indenoquinoline derivative that serves as a critical advanced intermediate in modern organic synthesis. Its intricate polycyclic structure and specific stereochemistry make it a valuable scaffold for developing novel compounds with targeted biological activity. This high-purity intermediate is primarily sought by pharmaceutical R&D and fine chemical sectors for the synthesis of potential drug candidates and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new chemical entities with potential therapeutic effects.
• Fluorinated Compound Synthesis: The presence of the fluorine atom makes it a valuable precursor for synthesizing other fluorinated organic molecules, which are important in agrochemical and material science applications.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals used in advanced material science and catalysis.
• Academic & Institutional Research: Serves as a reference compound or starting material for cutting-edge research in synthetic organic chemistry and chemical biology at universities and research institutes.

Basic Information

Product Name	1H-Indeno[5,4-f]quinoline-7-carboxylic acid, 3-fluoro-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1,4a,6a-triMethyl-2-oxo-, Methyl ester, (4aS,4bS,6aS,7S,9aS,9bS,11aR)-
CAS No.	606101-78-4
Molecular Formula	C22H26FNO3
Molecular Weight	371.45 g/mol
Synonyms	(4aS,4bS,6aS,7S,9aS,9bS,11aR)-3-Fluoro-1,4a,6a-trimethyl-2-oxo-1,2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid methyl ester; Methyl (4aS,4bS,6aS,7S,9aS,9bS,11aR)-3-fluoro-1,4a,6a-trimethyl-2-oxo-1,2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylate; 3-Fluoro-1,4a,6a-trimethyl-2-oxo-1,2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid methyl ester (stereoisomer); Fluorinated Indenoquinoline Methyl Ester Intermediate; CAS 606101-78-4
EINECS	Contact for details

Quality Control

This product is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Our quality assurance includes comprehensive analytical testing via HPLC, GC, NMR, and MS to confirm identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.