Description

Picras-3-en-21-oic acid, 13, 20-epoxy-3,11,12-trihydroxy-15-[ (4-hydroxy-3, 4-dimethyl-1-oxo-2-pentenyl)oxy]-2,16-dioxo-, methyl ester, [11.beta.,12.alpha.,15.beta.(E)]- is a complex, highly functionalized diterpenoid derivative with significant biological and chemical research interest. This compound matters as a valuable advanced intermediate or reference standard for pharmaceutical development and natural product chemistry studies. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical sectors for exploring novel synthetic pathways and bioactive molecule libraries.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related natural product extracts or synthetic batches.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to investigate the core diterpenoid scaffold for new biological activities.
• Natural Product Synthesis: Acts as a target molecule or intermediate in the total synthesis of complex quassinoids and related terpenoids.
• Biochemical Research: Utilized as a probe or inhibitor in enzymatic studies to understand specific biological pathways.
• Academic Research: Fundamental studies in organic synthesis, focusing on stereoselective reactions and complex molecule construction.

Basic Information

Product Name	Picras-3-en-21-oic acid, 13, 20-epoxy-3,11,12-trihydroxy-15-[ (4-hydroxy-3, 4-dimethyl-1-oxo-2-pentenyl)oxy]-2,16-dioxo-, methyl ester, [11.beta.,12.alpha.,15.beta.(E)]-
CAS No.	25514-30-1
Molecular Formula	C28H34O12
Molecular Weight	562.57 g/mol
Synonyms	Methyl (E)-15-[(4-Hydroxy-3,4-dimethyl-1-oxopent-2-en-2-yl)oxy]-13,20-epoxy-3,11,12-trihydroxy-2,16-dioxopicras-3-en-21-oate; (11β,12α,15β)-Isomer; A derivative of Quassin; Nigakilactone F derivative; Diterpenoid ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and MS for identity confirmation and purity assessment. Certificates of Analysis (COA) detailing batch-specific results are available upon request. For research and development purposes, we can provide material tailored to specific purity requirements, supported by comprehensive analytical data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.