Description

1,5-Cyclooctadiene{(4S)-(+)-2-[(5S)-6-(diphenylphosphino)spiro[4.4]nona-1.6-dien-1-yl]-4,5-dihydro-4-phenyloxazole}iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borate, 97% (S,S)-(COD)Ir[Ph-Spin is a high-purity, chiral iridium(I) complex featuring a spirocyclic phosphine-oxazoline (SpinPHOX) ligand, designed for advanced asymmetric catalysis. This compound matters because it serves as a highly efficient and enantioselective catalyst for challenging hydrogenation and other transition metal-catalyzed reactions, enabling the synthesis of optically pure intermediates. It is critically needed by research and development laboratories and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel chiral molecules.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Enables the production of single-enantiomer active pharmaceutical ingredients (APIs) and key chiral building blocks.
• Fine Chemical Manufacturing: Applied in the synthesis of specialty chemicals, flavors, and fragrances requiring high optical purity.
• Methodology Development: Used in academic and industrial R&D for developing new catalytic asymmetric transformations.
• Agrochemical Synthesis: For creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand Evaluation & Screening: Serves as a benchmark catalyst in high-throughput screening for new asymmetric processes.

Basic Information

Item	Details
Product Name	1,5-Cyclooctadiene{(4S)-(+)-2-[(5S)-6-(diphenylphosphino)spiro[4.4]nona-1.6-dien-1-yl]-4,5-dihydro-4-phenyloxazole}iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borate, 97% (S,S)-(COD)Ir[Ph-Spin
CAS No.	1194050-21-9
Molecular Formula	C81H60BF24IrNOP
Molecular Weight	~1745.1 g/mol
Synonyms	(S,S)-(COD)Ir[Ph-Spin] BArF; Iridium(I) (S,S)-[6-(Diphenylphosphino)spiro[4.4]nona-1,6-dien-1-yl]-4,5-dihydro-4-phenyl-2-oxazolyl-κN,κP] (1,5-cyclooctadiene) tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; (S,S)-Ir(COD)(SpinPHOX) BArF; Chiral Iridium-SpinPHOX Catalyst; (S,S)-Iridium SpinPHOX complex; Asymmetric Iridium Catalyst; Ir-SpinPHOX BArF Salt; (S,S)-[Ir(COD)(SpinPHOX)]BArF
EINECS	Contact for details

Quality Control

Our 1,5-Cyclooctadiene{(4S)-(+)-2-[(5S)-6-(diphenylphosphino)spiro[4.4]nona-1.6-dien-1-yl]-4,5-dihydro-4-phenyloxazole}iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borate, 97% is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements of catalysis research. Each lot is supplied with a comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral integrity. Our quality system is designed to support cGMP for pharmaceutical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability. This material is hygroscopic (moisture-sensitive) and easily oxidized; ensure containers are sealed immediately after use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Orange to red crystalline or amorphous solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Iridium Content	Contact for details
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.