Description

Oxireno(13,14)cyclotetradeca(1,2-b)furan-13(1aH)-one, 7,11-bis(acetylo xy)-2,3,6,7,10,11,11a,12,14a,14b-decahydro-1a,9-dimethyl-12-methylene- , (1aR*,4E,7S*,8E,11S*,11aR*,14aR*,14bS*)-(+)- is a complex, high-purity synthetic intermediate with a defined stereochemistry, identified by CAS No. 145038-59-1. This compound is valued for its role as a key building block in advanced organic synthesis, particularly for the development of novel pharmacologically active molecules. It is essential for R&D and production teams in the pharmaceutical and fine chemical industries seeking to create complex, stereospecific target compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those with fused polycyclic structures.
• Advanced Organic Synthesis: Serves as a sophisticated chiral building block for constructing natural product analogs and other stereochemically defined molecules in research laboratories.
• Medicinal Chemistry Research: Used in the discovery and optimization of new chemical entities (NCEs) targeting various disease pathways.
• Process Chemistry Development: Employed in scaling up synthetic routes from milligram to kilogram scale for preclinical and clinical trial material production.
• Fine Chemical Production: Integral to the manufacture of high-value, low-volume specialty chemicals for advanced material and agrochemical research.

Basic Information

Product Name	Oxireno(13,14)cyclotetradeca(1,2-b)furan-13(1aH)-one, 7,11-bis(acetylo xy)-2,3,6,7,10,11,11a,12,14a,14b-decahydro-1a,9-dimethyl-12-methylene- , (1aR*,4E,7S*,8E,11S*,11aR*,14aR*,14bS*)-(+)-
CAS No.	145038-59-1
Molecular Formula	C22H30O6
Molecular Weight	390.47 g/mol
Synonyms	(+)-7,11-Diacetoxy-1a,9-dimethyl-12-methylenedodecahydro-4,8-bis(methylene)cyclodeca[1,2-b:6,5-b']difuran-13(1aH)-one; 7,11-Diacetoxy-1a,9-dimethyl-12-methylenedodecahydro-4,8-bis(methylene)cyclodeca[1,2-b:6,5-b']difuran-13(1aH)-one; A complex taxane derivative intermediate; (1aR*,4E,7S*,8E,11S*,11aR*,14aR*,14bS*)-7,11-Bis(acetyloxy)-2,3,6,7,10,11,11a,12,14a,14b-decahydro-1a,9-dimethyl-12-methylene-4,8-methanooxireno[13,14]cyclotetradeca[1,2-b]furan-13(1aH)-one
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems. We employ state-of-the-art analytical techniques, including HPLC, GC, and NMR, to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound is easily oxidized; prolonged exposure to air should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.