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(1aR)-1,1aα,1bβ,4,4a,7aα,7b,8,9,9a-Decahydro-3-hydroxymethyl-5-oxo-1,1,6,8α-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulene-4aβ,7bα,9α,9aβ-tetrol 9-acetate 9a-laurate CAS NO 16675-05-1
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CAS No.:16675-05-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(1aR)-1,1aα,1bβ,4,4a,7aα,7b,8,9,9a-Decahydro-3-hydroxymethyl-5-oxo-1,1,6,8α-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulene-4aβ,7bα,9α,9aβ-tetrol 9-acetate 9a-laurate is a high-purity, semi-synthetic diterpenoid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chemical intermediate for synthesizing novel bioactive molecules, offering a complex, functionalized core structure. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating new therapeutic agents.
Application
- Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
- Chemical Reference Standard: Used for analytical method development, validation, and quality control in laboratories requiring high-purity benchmarks.
- Medicinal Chemistry Research: Provides a structurally complex scaffold for structure-activity relationship (SAR) studies and lead optimization.
- Biochemical Research: Employed in studies investigating biological pathways and enzyme interactions due to its specific stereochemistry.
- Fine Chemical Synthesis: Acts as a precursor for the production of other specialized diterpenoid derivatives and analogs.
Basic Information
| Item | Details |
|---|---|
| Product Name | (1aR)-1,1aα,1bβ,4,4a,7aα,7b,8,9,9a-Decahydro-3-hydroxymethyl-5-oxo-1,1,6,8α-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulene-4aβ,7bα,9α,9aβ-tetrol 9-acetate 9a-laurate |
| CAS No. | 16675-05-1 |
| Molecular Formula | C₃₅H₅₄O₈ |
| Molecular Weight | 602.80 g/mol |
| Synonyms | 9-Acetyl-9a-lauryl taxinine J; Taxinine J 9-acetate 9a-laurate; 9-Acetoxy-9a-lauryloxytaxinine J; (1aR,4aS,7bS,9S,9aS)-9-(Acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b,9,9a-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one 9a-dodecanoate; Taxusin derivative; Diterpenoid laurate ester |
| EINECS | Contact for details |
Quality Control
Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP standards for materials intended for pharmaceutical research applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area. For long-term storage, consider inert gas purging to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 95.0% |
| Related Substances (HPLC) | Total impurities ≤ 5.0% |
| Any single unknown impurity | ≤ 1.0% |
| Residual Solvents (GC) | Complies with ICH Q3C guidelines |
| Water Content (KF) | ≤ 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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