Description

1-Bromo-2-tert-Butoxy-4-Fluorobenzene is a high-purity, multi-functional aromatic building block designed for advanced organic synthesis. This compound is valued for its unique substitution pattern, which provides strategic handles for further functionalization in complex molecule construction. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorobenzene moiety is critical for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals and organic semiconductors.
• Custom Chemical Synthesis: An essential building block for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	1-Bromo-2-tert-Butoxy-4-Fluorobenzene
CAS No.	960309-88-0
Molecular Formula	C10H12BrFO
Molecular Weight	247.11 g/mol
Synonyms	2-Bromo-1-tert-butoxy-4-fluorobenzene; 4-Fluoro-2-bromo-1-tert-butoxybenzene; 1-Bromo-2-(tert-butoxy)-4-fluorobenzene; 2-(tert-Butoxy)-4-fluorobromobenzene; 4-Fluoro-2-bromophenyl tert-butyl ether; tert-Butyl 4-fluoro-2-bromophenyl ether
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-2-tert-Butoxy-4-Fluorobenzene is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.