Description

5-Methyl-4-Nitro-3-Isoxazolecarboxylic Acid is a high-purity, functionalized isoxazole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of novel pharmaceuticals and agrochemicals, enabling the construction of complex heterocyclic frameworks. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for antibiotics and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the bioactive isoxazole core.
• Fine Chemical Production: Serves as a specialized building block for creating complex molecules in custom synthesis and contract manufacturing.
• Academic & Industrial Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential precursor for the synthesis of functional polymers or ligands with specific electronic properties.

Basic Information

Product Name	5-Methyl-4-Nitro-3-Isoxazolecarboxylic Acid
CAS No.	960225-75-6
Molecular Formula	C6H4N2O5
Molecular Weight	184.11 g/mol
Synonyms	4-Nitro-5-methyl-3-isoxazolecarboxylic acid; 3-Isoxazolecarboxylic acid, 5-methyl-4-nitro-; 5-Methyl-4-nitroisoxazole-3-carboxylic acid; MNICA; 960225-75-6; 5-Methyl-4-nitro-1,2-oxazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Methyl-4-Nitro-3-Isoxazolecarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial use. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.