Description

2-Acetylamino-3-(2,5-Difluorophenyl)Acrylic Acid is a specialized fluorinated acrylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both a difluorophenyl group and an acrylate moiety, enabling precise modifications in target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Acts as a monomer or precursor for synthesizing specialty polymers with tailored properties like chemical resistance or specific optical characteristics.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and labeled compounds for diagnostic and research applications.
• Fine Chemical Production: Serves as a versatile intermediate for custom synthesis and contract manufacturing of complex, high-value organic compounds.

Basic Information

Product Name	2-Acetylamino-3-(2,5-Difluorophenyl)Acrylic Acid
CAS No.	959246-37-8
Molecular Formula	C₁₁H₉F₂NO₃
Molecular Weight	241.19 g/mol
Synonyms	(2E)-2-Acetamido-3-(2,5-difluorophenyl)acrylic acid; 2-Acetamido-3-(2,5-difluorophenyl)propenoic acid; 2-Acetylamino-3-(2,5-difluorophenyl)-2-propenoic acid; (E)-2-Acetamido-3-(2,5-difluorophenyl)acrylic acid; 959246-37-8; 2-Acetamido-3-(2,5-difluorophenyl)acrylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Acetylamino-3-(2,5-Difluorophenyl)Acrylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from incompatible materials such as strong bases and oxidizing agents. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.