Description

1H-Imidazole-4-Carboxylic Acid, 5-Fluoro-, Propyl Ester is a high-value fluorinated imidazole derivative, a crucial building block in advanced organic synthesis. This compound matters for its role in constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced biological activity and specific physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting enzymes and receptors where the imidazole scaffold is pharmacologically active.
• Agrochemical Synthesis: Used in the production of advanced fungicides, herbicides, and plant growth regulators, leveraging the fluorine atom for improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers, where fluorinated heterocycles can tune electronic properties.
• Chemical Biology Probes: Utilized to develop molecular probes and labeled compounds for studying biological mechanisms and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1H-Imidazole-4-Carboxylic Acid, 5-Fluoro-, Propyl Ester
CAS No.	959088-25-6
Molecular Formula	C7H9FN2O2
Molecular Weight	172.16 g/mol
Synonyms	5-Fluoro-1H-imidazole-4-carboxylic acid propyl ester; Propyl 5-fluoro-1H-imidazole-4-carboxylate; 5-Fluoro-1H-imidazole-4-carboxylic acid n-propyl ester; 1H-Imidazole-4-carboxylic acid, 5-fluoro-, propyl ester; 959088-25-6; 5-Fluoroimidazole-4-carboxylic acid propyl ester; Propyl 5-fluoroimidazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-4-Carboxylic Acid, 5-Fluoro-, Propyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and compliance with REACH regulations ensures a reliable supply for global research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is stable under inert atmosphere but should be handled and stored away from strong bases and incompatible materials. Keep container tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.