Description

(3-Difluoromethoxy-Benzyl)-Methyl-Amine is a high-purity, specialized organic amine building block featuring a difluoromethoxy-substituted benzyl group. This compound is valued for its role as a critical intermediate in the synthesis of advanced pharmaceutical candidates and agrochemicals, where its unique fluorine-containing structure imparts desirable metabolic stability and bioavailability. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the difluoromethoxy group for enhanced biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Intermediate in the production of advanced polymers and functional materials requiring fluorine incorporation for specific chemical resistance or surface properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Product Name	(3-Difluoromethoxy-Benzyl)-Methyl-Amine
CAS No.	958863-69-9
Molecular Formula	C9H11F2NO
Molecular Weight	187.19 g/mol
Synonyms	N-Methyl-1-[3-(difluoromethoxy)phenyl]methanamine; 1-[3-(Difluoromethoxy)phenyl]-N-methylmethanamine; 3-[(Methylamino)methyl]phenyl difluoromethyl ether; α-(Methylamino)-3-(difluoromethoxy)toluene; N-Methyl[3-(difluoromethoxy)benzyl]amine; (3-Difluoromethoxybenzyl)methylamine; 958863-69-9 (CAS)
EINECS	Contact for details

Quality Control

Our (3-Difluoromethoxy-Benzyl)-Methyl-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are sealed when not in use and stored away from heat sources and open flame. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.