Description

1-Bromo-2-Fluoro-3-Iodobenzene is a highly functionalized halogenated benzene derivative, serving as a versatile and valuable building block in advanced organic synthesis. Its distinct substitution pattern makes it a critical intermediate for constructing complex molecules where precise regiochemistry is required. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorine and iodine atoms can modulate biological activity and stability.
• Material Science Research: Building block for creating organic electronic materials, liquid crystals, and ligands for catalytic systems.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Sonogashira couplings, enabling the formation of new carbon-carbon bonds.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for imaging and diagnostic applications due to its halogen handles.
• Academic & Contract Research: Essential reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	1-Bromo-2-Fluoro-3-Iodobenzene
CAS No.	958458-89-4
Molecular Formula	C6H3BrFI
Molecular Weight	300.90 g/mol
Synonyms	2-Fluoro-3-iodo-1-bromobenzene; 3-Iodo-2-fluoro-1-bromobenzene; 1-Bromo-2-fluoro-3-iodobenzene; Benzene, 1-bromo-2-fluoro-3-iodo-; 2-Fluoro-3-iodobromobenzene; 3-Bromo-2-fluoro-1-iodobenzene (isomer); 958458-89-4 (CAS)
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Fluoro-3-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.