Description

1-Bromo-4-(3-Fluoro-Propoxy)-Benzene is a high-value aromatic ether building block featuring both bromine and fluorine substituents, offering versatile reactivity for advanced synthesis. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where its halogenated structure enables precise molecular modifications. It is primarily utilized in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as Suzuki cross-coupling reactions and the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings to form biaryl structures.
• Organic Synthesis & Research: Employed in academic and industrial R&D for constructing complex molecular architectures in medicinal and synthetic chemistry programs.
• Fluorine Chemistry Studies: Acts as a model compound for studying the influence of fluoroalkoxy groups on electronic properties and reactivity.

Basic Information

Product Name	1-Bromo-4-(3-Fluoro-Propoxy)-Benzene
CAS No.	958454-28-9
Molecular Formula	C9H10BrFO
Molecular Weight	233.08 g/mol
Synonyms	4-Bromo-1-(3-fluoropropoxy)benzene; 1-Bromo-4-(3-fluoropropoxy)benzene; p-Bromo(3-fluoropropoxy)benzene; Benzene, 1-bromo-4-(3-fluoropropoxy)-; 3-Fluoropropyl 4-bromophenyl ether; 4-(3-Fluoropropoxy)bromobenzene; 958454-28-9 (CAS)
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(3-Fluoro-Propoxy)-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.