Description

3-Hydroxytetrahydrofuran is a versatile heterocyclic building block and chiral intermediate of significant importance in fine chemical synthesis. Its bifunctional nature, containing both a hydroxyl group and a tetrahydrofuran ring, makes it a valuable precursor for pharmaceuticals, agrochemicals, and advanced materials. This compound is particularly sought after by R&D chemists and process development scientists in the pharmaceutical industry for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of antiviral drugs, antibiotics, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.
• Polymer Chemistry: Serves as a monomer or co-monomer for creating specialized polyethers and functional polymers.
• Ligand and Catalyst Preparation: Employed in the synthesis of chiral ligands for asymmetric catalysis and metal complexes.
• Organic Synthesis Reagent: Utilized in ring-opening reactions, etherifications, and as a protected diol equivalent in multi-step syntheses.
• Flavor and Fragrance Industry: Potential intermediate for the synthesis of certain lactone and furan-based aroma chemicals.

Basic Information

Product Name	3-Hydroxytetrahydrofuran
CAS No.	453-20-3
Molecular Formula	C4H8O2
Molecular Weight	88.11 g/mol
Synonyms	3-Hydroxytetrahydrofuran; Tetrahydro-3-furanol; 3-THF-OH; 3-Hydroxyoxolane; 3-Oxolanol; (±)-3-Hydroxytetrahydrofuran; DL-3-Hydroxytetrahydrofuran; 3-Tetrahydrofuranol
EINECS	207-222-7

Quality Control

Our 3-Hydroxytetrahydrofuran is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP or research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.