Description

1-Chloro-2-(2-Chloroethyl)-3-Fluorobenzene is a high-purity, multi-functional halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both chloro and fluoro substituents on a benzene ring with a chloroethyl side chain, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials used in displays and lighting.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Negishi, or Buchwald-Hartwig amination to form complex biaryl structures.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, dyes, and functional polymers.
• Chemical Research & Development: A valuable reagent for methodological studies and exploring new synthetic pathways in academic and industrial labs.

Basic Information

Product Name	1-Chloro-2-(2-Chloroethyl)-3-Fluorobenzene
CAS No.	958027-86-6
Molecular Formula	C8H7Cl2F
Molecular Weight	193.04 g/mol
Synonyms	2-(2-Chloroethyl)-1-chloro-3-fluorobenzene; 3-Fluoro-1-chloro-2-(2-chloroethyl)benzene; 1-Chloro-2-(2-chloroethyl)-3-fluoro-benzene; Benzene, 1-chloro-2-(2-chloroethyl)-3-fluoro-; 958027-86-6; 2-Chloroethyl-3-fluoro-1-chlorobenzene
EINECS	Contact for details

Quality Control

Every batch of 1-Chloro-2-(2-Chloroethyl)-3-Fluorobenzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by GC/HPLC), identity confirmation, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.