Description

2-Chloro-5-(1H-Pyrazol-1-Yl)Benzoic Acid is a high-value benzoic acid derivative functionalized with a chloropyrazole moiety, serving as a critical synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and active ingredient synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug discovery.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for functional monomers or ligands in the development of advanced polymers and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized as a scaffold or linker in the design of chemical probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for custom synthesis projects requiring specific chloropyrazole-benzoic acid motifs.

Basic Information

Product Name	2-Chloro-5-(1H-Pyrazol-1-Yl)Benzoic Acid
CAS No.	957509-90-9
Molecular Formula	C10H7ClN2O2
Molecular Weight	222.63 g/mol
Synonyms	2-Chloro-5-(1H-pyrazol-1-yl)benzoic acid; 5-(1H-Pyrazol-1-yl)-2-chlorobenzoic acid; Benzoic acid, 2-chloro-5-(1H-pyrazol-1-yl)-; 2-Chloro-5-(1-pyrazolyl)benzoic Acid; 957509-90-9; 2-Chloro-5-pyrazol-1-yl-benzoic acid; 2-Chloro-5-(pyrazol-1-yl)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(1H-Pyrazol-1-Yl)Benzoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.