Description

Methyl 3'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Carboxylate is a high-purity, functionalized biphenyl derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the trifluoromethyl-substituted biphenyl scaffold, which is a privileged structure for imparting desirable physicochemical properties to target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting metabolic diseases, CNS disorders, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of specialty electronic chemicals for displays and organic light-emitting diodes, leveraging its rigid biphenyl core.
• Organic Synthesis & Catalysis: Acts as a versatile synthon in cross-coupling reactions (e.g., Suzuki, Heck) and as a ligand precursor in catalytic systems.
• Material Science Research: Employed in the development of advanced polymers, coatings, and functional materials requiring specific aromatic and fluorinated components.

Basic Information

Product Name	Methyl 3'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Carboxylate
CAS No.	957207-59-9
Molecular Formula	C15H11F3O2
Molecular Weight	280.24 g/mol
Synonyms	[1,1'-Biphenyl]-4-carboxylic acid, 3'-(trifluoromethyl)-, methyl ester; Methyl 3'-(trifluoromethyl)biphenyl-4-carboxylate; 4'-Methoxycarbonyl-3'-(trifluoromethyl)biphenyl; Methyl 4'-(3-trifluoromethylphenyl)benzoate; 3'-Trifluoromethylbiphenyl-4-carboxylic acid methyl ester; 957207-59-9; Biphenyl-4-carboxylic acid, 3'-(trifluoromethyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.