Description

Benzene, 4-(Chloromethyl)-1-Cyclohexyl-2-(Trifluoromethyl)- is a specialized fluorinated and chlorinated aromatic building block with a unique cyclohexyl substituent. This compound matters as a high-value intermediate for synthesizing advanced molecules in pharmaceutical and agrochemical research, offering versatile sites for further functionalization. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Active Ingredient Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group's metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a precursor for fluorinated aromatic cores in electronic and display material applications.
• Advanced Polymer Modification: Employed to introduce fluorinated and chlorinated phenyl groups into polymer chains to alter surface properties and chemical resistance.
• Cross-Coupling Reactions: The chloromethyl and aryl halide functionalities make it a valuable substrate in Suzuki, Heck, and other palladium-catalyzed coupling reactions.
• Chemical Biology Probe Development: Utilized as a scaffold for creating fluorescent tags or affinity probes due to its derivatizable handles.

Basic Information

Product Name	Benzene, 4-(Chloromethyl)-1-Cyclohexyl-2-(Trifluoromethyl)-
CAS No.	957205-24-2
Molecular Formula	C14H16ClF3
Molecular Weight	276.73 g/mol
Synonyms	1-Chloromethyl-4-cyclohexyl-3-(trifluoromethyl)benzene; 4-(Chloromethyl)-1-cyclohexyl-2-(trifluoromethyl)benzene; 3-(Trifluoromethyl)-4-(chloromethyl)-1-cyclohexylbenzene; 1-Cyclohexyl-4-(chloromethyl)-2-(trifluoromethyl)benzene; [1,1'-Biphenyl]-4-carbonitrile, 3'-chloro-4-fluoro-; (4-(Chloromethyl)-2-(trifluoromethyl)phenyl)cyclohexane
EINECS	Contact for details

Quality Control

Our Benzene, 4-(Chloromethyl)-1-Cyclohexyl-2-(Trifluoromethyl)- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.