Description

2-(Difluoromethoxy)-1-Fluoro-4-(Trifluoromethyl)Benzene is a high-value fluorinated aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring multiple fluorine atoms and a difluoromethoxy group, makes it a critical intermediate for developing novel compounds with enhanced properties. This specialty chemical is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for creating next-generation active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting metabolic and central nervous system diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atoms improve biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorine-containing liquid crystals used in high-performance displays (LCDs) due to its influence on dielectric anisotropy and viscosity.
• Organic Electronics: Employed in the research and production of materials for organic light-emitting diodes (OLEDs) and semiconductor layers.
• Polymer Modification: Acts as a monomer or modifier to introduce fluorine into polymers, enhancing their chemical resistance, thermal stability, and surface properties.
• Chemical Research & Development: A versatile reagent in academic and industrial labs for exploring new reactions and creating complex fluorinated molecules for various applications.

Basic Information

Product Name	2-(Difluoromethoxy)-1-Fluoro-4-(Trifluoromethyl)Benzene
CAS No.	957146-67-7
Molecular Formula	C9H4F6O
Molecular Weight	242.12 g/mol
Synonyms	1-Fluoro-2-(difluoromethoxy)-4-(trifluoromethyl)benzene; 2-(Difluoromethoxy)-α,α,α,1-tetrafluorotoluene; Benzene, 2-(difluoromethoxy)-1-fluoro-4-(trifluoromethyl)-; 1-Fluoro-4-trifluoromethyl-2-difluoromethoxybenzene; DFMFB (abbreviation)
EINECS	Contact for details

Quality Control

Our 2-(Difluoromethoxy)-1-Fluoro-4-(Trifluoromethyl)Benzene is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are properly sealed and stored upright. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.5%
Water Content (KF)	≤ 0.1%
Density (20°C)	~1.5 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.