Description

4-Bromo-1-(2-Nitrophenyl)-1H-Pyrazole is a high-purity, synthetically valuable heterocyclic building block. This compound matters as a key intermediate in the development of advanced pharmaceutical agents and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for use in cross-coupling reactions and as a precursor to novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development and optimization of new pesticides and herbicides, where the pyrazole and nitroaryl motifs are common pharmacophores.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Chemical Synthesis: Employed in Suzuki-Miyaura, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to introduce the bromopyrazole moiety into more complex molecules.
• Academic & Contract Research: Essential for fundamental organic chemistry research and for contract research organizations (CROs) supporting client discovery projects.

Basic Information

Product Name	4-Bromo-1-(2-Nitrophenyl)-1H-Pyrazole
CAS No.	957034-96-7
Molecular Formula	C9H6BrN3O2
Molecular Weight	268.07 g/mol
Synonyms	4-Bromo-1-(2-nitrophenyl)-1H-pyrazole; 1-(2-Nitrophenyl)-4-bromo-1H-pyrazole; 4-Bromo-1-(o-nitrophenyl)-1H-pyrazole; 957034-96-7; 4-Bromo-1-(2-nitrophenyl)pyrazole; 1H-Pyrazole, 4-bromo-1-(2-nitrophenyl)-; 4-Br-1-(2-NO2-Ph)-Pyrazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-(2-Nitrophenyl)-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.