Description

4-Nitro-1-Oxido-Pyridine is a versatile nitro-substituted pyridine N-oxide derivative, serving as a critical synthetic intermediate and building block in advanced organic chemistry. Its unique structure provides a reactive site for nucleophilic aromatic substitution and functional group transformations, enabling the synthesis of complex heterocyclic compounds. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its bioactive nitro-heterocyclic scaffold.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized N-oxide ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Building block for synthesizing functionalized polymers, dyes, and photoactive materials.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and methodologies in academic and industrial R&D laboratories.

Basic Information

Product Name	4-Nitro-1-Oxido-Pyridine
CAS No.	1124-82-9
Molecular Formula	C5H4N2O3
Molecular Weight	140.10 g/mol
Synonyms	4-Nitropyridine N-Oxide; 4-Nitropyridine 1-Oxide; 1-Oxido-4-nitropyridine; Pyridine, 4-nitro-, 1-oxide; 4-Nitropyridine Oxide; 4-NPO; 4-Nitropyridinium N-Oxide
EINECS	214-395-5

Quality Control

Our 4-Nitro-1-Oxido-Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.