Description

1-Ethyl-4-Iodo-1H-Pyrazole-3-Carboxylic Acid is a high-value, multi-functional heterocyclic building block featuring a reactive iodine substituent and a carboxylic acid group. This compound is essential for the synthesis of complex molecules, enabling the introduction of the pyrazole scaffold and facilitating further derivatization via cross-coupling or substitution reactions. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Acts as a building block for creating functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring specific, functionalized pyrazole derivatives.

Basic Information

Product Name	1-Ethyl-4-Iodo-1H-Pyrazole-3-Carboxylic Acid
CAS No.	956909-60-7
Molecular Formula	C6H7IN2O2
Molecular Weight	266.04 g/mol
Synonyms	4-Iodo-1-ethyl-1H-pyrazole-3-carboxylic acid; 1-Ethyl-4-iodopyrazole-3-carboxylic acid; 1H-Pyrazole-3-carboxylic acid, 1-ethyl-4-iodo-; 956909-60-7; 1-Ethyl-4-iodo-1H-pyrazole-3-carboxylic acid; 3-Carboxy-1-ethyl-4-iodopyrazole
EINECS	Contact for details

Quality Control

Our 1-Ethyl-4-Iodo-1H-Pyrazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.