Description

4'-Chloro-4-Fluoro-3-Nitrobenzophenone is a high-purity, multi-functional nitro-aromatic ketone building block essential for advanced organic synthesis. This compound matters because it provides a strategically halogenated and nitrated benzophenone core, enabling precise molecular construction in complex chemical pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and inflammatory conditions.
• Agrochemical Synthesis: Serves as a critical building block for developing new herbicides and pesticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, substituted aromatic structure.
• Dye & Pigment Intermediate: Functions as a starting material for synthesizing advanced colorants and photographic chemicals.
• Cross-Coupling Reactions: The halogen substituents make it a valuable substrate for palladium-catalyzed Suzuki, Heck, and Buchwald-Hartwig amination reactions.
• Nitro-Reduction Chemistry: The nitro group can be selectively reduced to an amine, unlocking a versatile aniline derivative for further functionalization.

Basic Information

Product Name	4'-Chloro-4-Fluoro-3-Nitrobenzophenone
CAS No.	956474-49-0
Molecular Formula	C13H7ClFNO3
Molecular Weight	279.65 g/mol
Synonyms	4-Chloro-4'-fluoro-3-nitrobenzophenone; (4-Chlorophenyl)(4-fluoro-3-nitrophenyl)methanone; 1-(4-Chlorophenyl)-2-(4-fluoro-3-nitrophenyl)ethanone (common misnomer); Benzophenone, 4'-chloro-4-fluoro-3-nitro-; 956474-49-0; 4-Fluoro-3-nitro-4'-chlorobenzophenone; 3-Nitro-4-fluoro-4'-chlorobenzophenone
EINECS	Contact for details

Quality Control

Our 4'-Chloro-4-Fluoro-3-Nitrobenzophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and scale-up. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.