Description

4''-Chloro-2''-Fluoroacetophenone CAS NO 175711-83-8 is a high-purity fluorinated and chlorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its unique halogenated structure makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine and chlorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Material Development: Serves as a building block for fluorinated liquid crystal compounds used in high-performance displays.
• Organic Electronic Materials: Intermediate in the synthesis of specialized monomers and polymers for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A valuable reagent for exploring new cross-coupling reactions and developing novel fluorination methodologies in academic and industrial R&D labs.
• Dye and Pigment Intermediate: Used in the synthesis of specialized halogenated dyes and pigments with improved lightfastness and color properties.

Basic Information

Item	Detail
Product Name	4''-Chloro-2''-Fluoroacetophenone
CAS No.	175711-83-8
Molecular Formula	C8H6ClFO
Molecular Weight	172.58 g/mol
Synonyms	1-(4-Chloro-2-fluorophenyl)ethanone; 4-Chloro-2-fluoroacetophenone; 2-Fluoro-4-chloroacetophenone; p-Chloro-o-fluoroacetophenone; 4'-Chloro-2'-fluoroacetophenone; 2-Fluoro-4'-chloroacetophenone; 4-Chloro-2-fluorophenyl methyl ketone; 1-Acetyl-4-chloro-2-fluorobenzene
EINECS	Contact for details

Quality Control

Our 4''-Chloro-2''-Fluoroacetophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.