Description

4-Methylsulphonylacetophenone is a high-purity organic intermediate characterized by its distinct acetophenone core functionalized with a methylsulfonyl group. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the creation of complex molecules with specific functionalities. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for synthesizing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the methylsulfonyl moiety can contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic semiconductors and photoactive materials for electronic applications.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.
• Academic and Industrial R&D: Utilized in research laboratories for method development and exploring new chemical reactions involving sulfone chemistry.

Basic Information

Product Name	4-Methylsulphonylacetophenone
CAS No.	10297-73-1
Molecular Formula	C9H10O3S
Molecular Weight	198.24 g/mol
Synonyms	1-[4-(Methylsulfonyl)phenyl]ethanone; 4'-Acetylphenyl methyl sulfone; 4-Acetylphenyl methyl sulfone; p-Acetylphenyl methyl sulfone; Methyl 4-acetylphenyl sulfone; 4-Methylsulfonylacetophenone; 4-(Methylsulfonyl)acetophenone; p-Methylsulfonylacetophenone
EINECS	Contact for details

Quality Control

Our 4-Methylsulphonylacetophenone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	142 - 146 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.