Description

1-(Pentafluorobenzyl)-1H-Pyrazol-4-Amine is a high-purity, fluorinated pyrazole derivative, a key building block in advanced organic synthesis. This compound is valued for its unique structure, which incorporates a pentafluorobenzyl group, making it an essential intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of new drug candidates, particularly in areas requiring fluorinated motifs for improved pharmacokinetics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the pentafluorobenzyl group can contribute to efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for designing specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1-(Pentafluorobenzyl)-1H-Pyrazol-4-Amine
CAS No.	956440-84-9
Molecular Formula	C10H6F5N3
Molecular Weight	263.17 g/mol
Synonyms	1-[(Pentafluorophenyl)methyl]-1H-pyrazol-4-amine; 4-Amino-1-(pentafluorobenzyl)pyrazole; 1H-Pyrazol-4-amine, 1-[(2,3,4,5,6-pentafluorophenyl)methyl]-; 1-(Pentafluorobenzyl)-4-aminopyrazole; 956440-84-9; 1-(Pentafluorobenzyl)-1H-pyrazol-4-ylamine
EINECS	Contact for details

Quality Control

Every batch of 1-(Pentafluorobenzyl)-1H-Pyrazol-4-Amine is manufactured under a strict quality management system. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and other critical parameters is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.