Description

1-[3-(Trifluoromethyl)Benzyl]-1H-Pyrazol-3-Amine is a high-value, fluorinated pyrazole derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its unique trifluoromethylbenzyl moiety, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the design and production of next-generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Acts as a precursor for specialty polymers and advanced materials requiring fluorinated aromatic components.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and ligands for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client-specific projects.

Basic Information

Product Name	1-[3-(Trifluoromethyl)Benzyl]-1H-Pyrazol-3-Amine
CAS No.	956395-93-0
Molecular Formula	C11H10F3N3
Molecular Weight	241.21 g/mol
Synonyms	1-[(3-Trifluoromethyl)benzyl]-1H-pyrazol-3-amine; 1-(3-(Trifluoromethyl)benzyl)-1H-pyrazol-3-amine; 3-Amino-1-[(3-trifluoromethyl)phenyl]methylpyrazole; 1H-Pyrazol-3-amine, 1-[[3-(trifluoromethyl)phenyl]methyl]-; 956395-93-0; α-(3-Amino-1H-pyrazol-1-yl)-3-(trifluoromethyl)benzyl alcohol (tautomer); 1-(3-Trifluoromethylbenzyl)-1H-pyrazol-3-ylamine
EINECS	Contact for details

Quality Control

Our 1-[3-(Trifluoromethyl)Benzyl]-1H-Pyrazol-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.