Description

2-[(2-Fluoro-4-Nitrophenoxy)Methyl]Tetrahydrofuran is a specialized fluorinated and nitrated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research, where the introduction of fluorine and nitro groups can dramatically alter biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and pesticides, where the fluoronitrophenoxy moiety can enhance efficacy and environmental profile.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for creating fluorinated aromatic cores used in electronic display technologies and organic semiconductors.
• Polymer Modification: Employed to introduce functional groups into polymer backbones, altering physical properties like solubility, thermal stability, and refractive index.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized nitro- and fluoro-containing dyes with unique color fastness and spectral properties.
• Cross-Coupling Reactions: The nitro and fluoro substituents make it a valuable substrate in palladium-catalyzed cross-coupling reactions for constructing biaryl systems.

Basic Information

Product Name	2-[(2-Fluoro-4-Nitrophenoxy)Methyl]Tetrahydrofuran
CAS No.	956015-51-3
Molecular Formula	C11H12FNO4
Molecular Weight	241.22 g/mol
Synonyms	2-[(2-Fluoro-4-nitrophenoxy)methyl]oxolane; Tetrahydro-2-[(2-fluoro-4-nitrophenoxy)methyl]furan; 2-(2-Fluoro-4-nitrophenoxymethyl)tetrahydrofuran; 2-((2-Fluoro-4-nitrophenoxy)methyl)tetrahydrofuran; Furan, tetrahydro-2-[(2-fluoro-4-nitrophenoxy)methyl]-; 956015-51-3; (2-Fluoro-4-nitrophenoxymethyl)tetrahydrofuran
EINECS	Contact for details

Quality Control

Our 2-[(2-Fluoro-4-Nitrophenoxy)Methyl]Tetrahydrofuran is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.