Description

1H-Indole, 6-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, multi-functional indole derivative containing a pinacol boronate ester group, making it a critical building block for modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to construct complex molecular architectures with precision.

Application

• Pharmaceutical Intermediate: A key synthon for constructing indole-based active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that incorporate the indole scaffold.
• Material Science Research: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers, where the indole unit modulates electronic properties.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for studying biological pathways and enzyme functions.
• Academic & Contract Research: A versatile reagent for methodology development and complex molecule synthesis in university and CRO laboratories worldwide.

Basic Information

Product Name	1H-Indole, 6-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	955979-12-1
Molecular Formula	C15H20BNO3
Molecular Weight	273.14 g/mol
Synonyms	6-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methoxy-1H-indole; 6-Methoxy-4-(pinacolboron)-1H-indole; 4-Borono-6-methoxy-1H-indole pinacol ester; 6-Methoxy-1H-indole-4-boronic acid pinacol ester; 4-(Pinacolatoboryl)-6-methoxy-1H-indole; CAS 955979-12-1
EINECS	Contact for details

Quality Control

Our production of 1H-Indole, 6-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.