Description

1-(2-Bromoethyl)-3-Fluoro-5-(Trifluoromethyl)Benzene is a high-value, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is engineered to serve as a critical intermediate in the development of complex molecules, offering versatile reactivity through its bromoethyl and trifluoromethyl substituents. It is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical industries for constructing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for advanced organic electronic materials due to its aromatic core and halogenated functional groups.
• Cross-Coupling Reactions: The bromoethyl side chain makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Fluorine Chemistry: An essential reagent for introducing fluorine-containing motifs into target molecules, a common strategy in modern drug design to improve metabolic stability and membrane permeability.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the custom synthesis of client-specific target molecules.

Basic Information

Product Name	1-(2-Bromoethyl)-3-Fluoro-5-(Trifluoromethyl)Benzene
CAS No.	955036-79-0
Molecular Formula	C9H7BrF4
Molecular Weight	271.05 g/mol
Synonyms	2-Bromo-1-(3-Fluoro-5-(trifluoromethyl)phenyl)ethane; 3-Fluoro-5-(trifluoromethyl)phenethyl bromide; 1-(2-Bromoethyl)-3-fluoro-5-(trifluoromethyl)benzene; 2-(3-Fluoro-5-(trifluoromethyl)phenyl)ethyl bromide; [2-(3-Fluoro-5-trifluoromethyl-phenyl)-ethyl]-bromide; 3-Fluoro-α,α,α-trifluoro-2-bromoethyltoluene
EINECS	Contact for details

Quality Control

Every batch of 1-(2-Bromoethyl)-3-Fluoro-5-(Trifluoromethyl)Benzene undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Our quality assurance protocol includes GC, HPLC, NMR, and MS analysis to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.