Description

1-(4-Fluorobenzyl)-2,5-Dihydro-1H-Pyrrole is a versatile fluorinated pyrroline derivative, a key heterocyclic building block in advanced organic synthesis. Its structure, featuring a reactive dihydropyrrole core and a fluorinated benzyl group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) agents and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis Building Block: Employed in medicinal chemistry for scaffold hopping and the construction of diverse heterocyclic libraries via cycloaddition or functional group transformations.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory research in fluorine chemistry.

Basic Information

Product Name	1-(4-Fluorobenzyl)-2,5-Dihydro-1H-Pyrrole
CAS No.	954416-86-5
Molecular Formula	C11H12FN
Molecular Weight	177.22 g/mol
Synonyms	1-[(4-Fluorophenyl)methyl]-2,5-dihydro-1H-pyrrole; 4-Fluorobenzyl-2,5-dihydro-1H-pyrrole; 1-(4-Fluorobenzyl)-2,5-dihydropyrrole; 2,5-Dihydro-1-(4-fluorobenzyl)-1H-pyrrole; 1H-Pyrrole, 2,5-dihydro-1-[(4-fluorophenyl)methyl]-
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorobenzyl)-2,5-Dihydro-1H-Pyrrole is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.