Description

3-Amino-4-tert-Butoxycarbonylamino-Benzoic Acid is a high-purity, multifunctional aromatic building block of significant importance in advanced organic synthesis. Its value lies in the dual-protected amine and carboxylic acid functionalities, which allow for selective and sequential derivatization under mild conditions. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring protected aniline derivatives.
• Peptide Mimetics & Conjugation: Used to incorporate aromatic, functionalized amino acid analogs into peptides and peptidomimetics for drug discovery.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the creation of functionalized polymers, dendrimers, and organic frameworks with tailored properties.
• Chemical Biology Probes: Useful for synthesizing labeled compounds and molecular probes for biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, protected aromatic amines.

Basic Information

Product Name	3-Amino-4-tert-Butoxycarbonylamino-Benzoic Acid
CAS No.	954238-52-9
Molecular Formula	C12H16N2O4
Molecular Weight	252.27 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]-3-aminobenzoic acid; 3-Amino-4-[(tert-butoxycarbonyl)amino]benzoic acid; 3-Amino-4-Boc-amino-benzoic acid; Boc-3,4-diaminobenzoic acid (Boc-DABA); Benzoic acid, 3-amino-4-[[(1,1-dimethylethoxy)carbonyl]amino]-; 4-(Boc-amino)-3-aminobenzoic acid; 3-Amino-4-(N-Boc-amino)benzoic Acid
EINECS	Contact for details

Quality Control

Our 3-Amino-4-tert-Butoxycarbonylamino-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.